Wentworth Miller (Michael Scofield)
Born in England, raised in Brooklyn, New York, graduate of Princeton University. Wentworth Miller is a compelling and critically acclaimed young actor whose credits span both television and feature film. After graduating from college with a degree in English Literature, Miller headed to Los Angeles to work in the development department of a small production company specializing in movies made for television.

Dominic Purcell (Lincoln Burrows)
Purcell grew up in Australia and attended the prestigious Australian Theatre for Young People. After beginning his training there, he attended the Western Australian Academy of Performing Arts alongside fellow actors Hugh Jackman and Frances O'Connor. After graduating, Purcell quickly landed a leading role on the Australian television series "Raw FM."

Rockmond Dunbar (Benjamin "C-Note" Miles Franklin)
Dunbar is best known for his leading role as Kenny Chadway on the critically-acclaimed television series Soul Food. On Prison Break, he played the role of a character who was discharged from the military and arrested for black market dealing. The underlying reason for his incarceration however, is implied to be for reporting the torture of a prisoner he had witnessed while on guard duty. Dunbar's other credits include several guest appearances in Earth 2, Felicity, The Pretender, Two Guys and a Girl and North Shore.

Sarah Wayne Callies (Sara Tancredi)
Raised in Honolulu, Callies is the daughter of two university professors. After graduating from Dartmouth College in 1999 with an undergraduate emphasis in Feminist Studies and a Senior Fellowship in Indigenous Theology, she attended Denver's National Theatre Conservatory to pursue her love of acting and to complete her Master of Fine Arts degree.

Amaury Nolasco (Fernando Sucre)
Amaury Nolasco, a native of Puerto Rico, studied biology full-time at the University of Puerto Rico. His plan to enroll in medical school and become a doctor was cut short when a director approached Nolasco and encouraged him to pursue acting. He was immediately cast in his first television commercial and began working consistently as an actor in Puerto Rico.

Robert Knepper (Theodore "T-Bag" Bagwell)
Robert Knepper owes his acting career in large part to his mother, who, when he was a child, worked in the props department for a community theater in Fremont, OH. This involvement sparked Knepper's interest in the arts, leading him to work in community theater and high school productions. He went on to study drama at Northwestern University.

William Fichtner (Alex Mahone)
As a member of the Circle Repertory Theatre, Fichtner won critical acclaim for his role in "The Fiery Furnace," directed by Norman Rene. He has also appeared on stage in "Raft of the Medusa" at the Minetta Lane Theatre, "The Years" at the Manhattan Theatre Club, "Clothes for a Summer Hotel" at the Williamstown Theatre festival and "Machinal" at The Public Theatre.

Michael Rapaport (Don Self) - season 4
In 1993 Michael Rapaport made his film debut in "Zebrahead," receiving critical acclaim for his genuine and confident portrayal of a Jewish teenager growing up in a predominantly African-American Detroit neighborhood. The performance garnered him an Independent Spirit Award nomination and the film itself won the 1993 Sundance Film Festival's Filmmaker's Trophy.

Chris Vance (James Whistler) - season 3
Although he's British born and bred, Chris Vance is well known in Australia as Sean Everleigh in the drama "All Saints". Chris was born December 1971 in the UK. His tv roles include Stingers, Blue Heelers and The Bill.

Wade Williams (Brad Bellick)
Williams, who has two sisters and one brother, was born and raised in Atlanta, and went to high school and college in Tulsa, OK. Although he had a passion for drama and music, he graduated high school intending to study medicine at the University of Tulsa. However, after signing up for voice lessons, Williams changed his career plans. He complemented his bachelor's degree in Theatrical Studies with an MFA in Acting from Rutgers' Mason Gross School of the Arts, where he studied under William Esper.

Jodi Lyn O’Keefe (Gretchen Morgan)
Born on 10th October 1978 in New Jersey, Jodi left Saint John Vianney High School during her sophomore year to move to Hollywood and pursue an acting career as she starred in "Another World". Jodi had to continue her high school education by mail as she rose to fame at the tender age of 17 as Cassidy Bridges in Nash Bridges and made her big screen debut in Halloween H20: 20 years later and She's All That. Jodi has a wide range in taste as she is a Nirvana fan, loves kickboxing but also enjoys painting teacups. 3 Doors Down fans may recognize Jodi in the music video "Let Me Go" in which she took the role of a stripper alongside Jesse Metcalfe.

Paul Adelstein (Paul Kellerman)
Paul Adelstein began his professional acting career at 20 when he joined John Cusack's commedia dell'arte troupe, New Crime Productions, in his native Chicago. After appearing in commedia versions of MaratlSade, Fear and Loathing in Las Vegas and The Balcony, among others, he began working with the renowned Steppenwolf Theatre Company, where he appeared in numerous productions, including A Clockwork Orange, directed by Terry Kinney; Horning Star, directed by Frank Galati; and A Soldier's Tale, a co-production of Steppenwolf Theatre and the Chicago Symphony Orchestra, featuring Pinchas Zuckerman.

Robin Tunney (Veronica Donovan) - season 1
Robin Tunney's versatility has not only landed her roles alongside such actors as Michael Douglas, Ed Harris, Arnold Schwarzenegger and Kyra Sedgwick, but has also made her a "treasured jewel" in the independent film world. With each edgy, powerful, comedic and sometimes quirky performance, she is defining herself as one of Hollywood's leading young actresses.

Jeff Perry (Terrence Steadman) - season 1

At a young age, his elder sister Jo took him to an audition at Ravinia Festivall where American Conservatory Theater was staging Luigi Pirandello's Six Characters in Search of an Author. He auditioned and got the part. He is one of the original co-founders of the Steppenwolf Theatre Company in Chicago, Illinois. Perry and schoolmates Gary Sinise and Terry Kinney started the company in a city church basement. It has since grown into a notable national theater company that includes John Malkovich, John Mahoney and Joan Allen. Perry remains an Executive Artistic Director along with co-founders Kinney & Sinise.